Intermediate Piperazine hydrate (1:1) 

It is mainly used to synthesize anti-tuberculosis and antibacterial drugs, which can be synthesized by synthesis of n-methyl piperazine, piperazine phosphate, piperazine sulfate, fluperacid, piperic acid, quinolone, and rifamid. The pharmaceutical intermediates are mainly used for the production of piperazine, citric acid and piperazine citrate, as well as fluphenazine, strong pain, and rifampicin.Piperazine hexahydrate is soluble in ethanol and is mixed with glacial acetic acid, which is precipitated out of piperazine acetate, and is used to synthesize the hydrogenated prednisolone sodium phosphate.Piperazine hexahydrate and acetic anhydride were used to control the intermediate acetylpiperazine.